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From science to business: translating live biotherapeutic products to the clinic
At Pulmobiotics, we engineer bacteria for the treatment of respiratory diseases. Here, we outline how we designed MycoChassis — an attenuated bacterium strain obtained by genome engineering of Mycoplasma pneumoniae (a human lung pathogen) — and discuss the challenges on the road to its clinical tran...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236387/ https://www.ncbi.nlm.nih.gov/pubmed/37359770 http://dx.doi.org/10.1038/s44222-023-00078-w |
| _version_ | 1785052907810324480 |
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| author | Lluch-Senar, Maria |
| author_facet | Lluch-Senar, Maria |
| author_sort | Lluch-Senar, Maria |
| collection | PubMed |
| description | At Pulmobiotics, we engineer bacteria for the treatment of respiratory diseases. Here, we outline how we designed MycoChassis — an attenuated bacterium strain obtained by genome engineering of Mycoplasma pneumoniae (a human lung pathogen) — and discuss the challenges on the road to its clinical translation. |
| format | Online Article Text |
| id | pubmed-10236387 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-102363872023-06-06 From science to business: translating live biotherapeutic products to the clinic Lluch-Senar, Maria Nat Rev Bioeng Down to Business At Pulmobiotics, we engineer bacteria for the treatment of respiratory diseases. Here, we outline how we designed MycoChassis — an attenuated bacterium strain obtained by genome engineering of Mycoplasma pneumoniae (a human lung pathogen) — and discuss the challenges on the road to its clinical translation. Nature Publishing Group UK 2023-06-02 /pmc/articles/PMC10236387/ /pubmed/37359770 http://dx.doi.org/10.1038/s44222-023-00078-w Text en © Springer Nature Limited 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | Down to Business Lluch-Senar, Maria From science to business: translating live biotherapeutic products to the clinic |
| title | From science to business: translating live biotherapeutic products to the clinic |
| title_full | From science to business: translating live biotherapeutic products to the clinic |
| title_fullStr | From science to business: translating live biotherapeutic products to the clinic |
| title_full_unstemmed | From science to business: translating live biotherapeutic products to the clinic |
| title_short | From science to business: translating live biotherapeutic products to the clinic |
| title_sort | from science to business: translating live biotherapeutic products to the clinic |
| topic | Down to Business |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236387/ https://www.ncbi.nlm.nih.gov/pubmed/37359770 http://dx.doi.org/10.1038/s44222-023-00078-w |
| work_keys_str_mv | AT lluchsenarmaria fromsciencetobusinesstranslatinglivebiotherapeuticproductstotheclinic |