Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access

Typhoid is an enteric disease caused by Salmonella Typhi. Like many febrile illnesses, typhoid presents with nonspecific symptoms. In routine healthcare settings in low- and middle-income countries, typhoid fever is suspected and treated empirically. Though many diagnostic tests are available for ty...

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Autores principales: Sapkota, Jyotshna, Roberts, Tamalee, Basnyat, Buddha, Baker, Stephen, Hampton, Lee M, Dittrich, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Charting the Course Supplement
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236505/
https://www.ncbi.nlm.nih.gov/pubmed/37274534
http://dx.doi.org/10.1093/ofid/ofad120
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author Sapkota, Jyotshna
Roberts, Tamalee
Basnyat, Buddha
Baker, Stephen
Hampton, Lee M
Dittrich, Sabine
author_facet Sapkota, Jyotshna
Roberts, Tamalee
Basnyat, Buddha
Baker, Stephen
Hampton, Lee M
Dittrich, Sabine
author_sort Sapkota, Jyotshna
collection PubMed
description Typhoid is an enteric disease caused by Salmonella Typhi. Like many febrile illnesses, typhoid presents with nonspecific symptoms. In routine healthcare settings in low- and middle-income countries, typhoid fever is suspected and treated empirically. Though many diagnostic tests are available for typhoid diagnosis, there are currently no diagnostic tests that meet ideal requirements for sensitivity, specificity, speed, and cost-effectiveness. With introduction of typhoid conjugate vaccine, it is essential to explore the current and future typhoid approach in the context of use case and access to ensure their utilization for disease control.
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spelling pubmed-102365052023-06-03 Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access Sapkota, Jyotshna Roberts, Tamalee Basnyat, Buddha Baker, Stephen Hampton, Lee M Dittrich, Sabine Open Forum Infect Dis Charting the Course Supplement Typhoid is an enteric disease caused by Salmonella Typhi. Like many febrile illnesses, typhoid presents with nonspecific symptoms. In routine healthcare settings in low- and middle-income countries, typhoid fever is suspected and treated empirically. Though many diagnostic tests are available for typhoid diagnosis, there are currently no diagnostic tests that meet ideal requirements for sensitivity, specificity, speed, and cost-effectiveness. With introduction of typhoid conjugate vaccine, it is essential to explore the current and future typhoid approach in the context of use case and access to ensure their utilization for disease control. Oxford University Press 2023-06-02 /pmc/articles/PMC10236505/ /pubmed/37274534 http://dx.doi.org/10.1093/ofid/ofad120 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Charting the Course Supplement
Sapkota, Jyotshna
Roberts, Tamalee
Basnyat, Buddha
Baker, Stephen
Hampton, Lee M
Dittrich, Sabine
Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access
title Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access
title_full Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access
title_fullStr Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access
title_full_unstemmed Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access
title_short Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access
title_sort diagnostics for typhoid fever: current perspectives and future outlooks for product development and access
topic Charting the Course Supplement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236505/
https://www.ncbi.nlm.nih.gov/pubmed/37274534
http://dx.doi.org/10.1093/ofid/ofad120
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