Cargando…

Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem

Typhoid fever is a significant global health problem that impacts people living in areas without access to clean water and sanitation. However, collaborative international partnerships and new research have improved both knowledge of the burden in countries with endemic disease and the tools for imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jessie, Long, Jessica E, Vannice, Kirsten, Shewchuk, Tanya, Kumar, Supriya, Duncan Steele, A, Zaidi, Anita K M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236514/
https://www.ncbi.nlm.nih.gov/pubmed/37274535
http://dx.doi.org/10.1093/ofid/ofad055
_version_ 1785052947936182272
author Chen, Jessie
Long, Jessica E
Vannice, Kirsten
Shewchuk, Tanya
Kumar, Supriya
Duncan Steele, A
Zaidi, Anita K M
author_facet Chen, Jessie
Long, Jessica E
Vannice, Kirsten
Shewchuk, Tanya
Kumar, Supriya
Duncan Steele, A
Zaidi, Anita K M
author_sort Chen, Jessie
collection PubMed
description Typhoid fever is a significant global health problem that impacts people living in areas without access to clean water and sanitation. However, collaborative international partnerships and new research have improved both knowledge of the burden in countries with endemic disease and the tools for improved surveillance, including environmental surveillance. Two typhoid conjugate vaccines (TCVs) have achieved World Health Organization prequalification, with several more in the development pipeline. Despite hurdles posed by the coronavirus disease 2019 pandemic, multiple TCV efficacy trials have been conducted in high-burden countries, and data indicate that TCVs provide a high degree of protection from typhoid fever, are safe to use in young children, provide lasting protection, and have the potential to combat typhoid antimicrobial resistance. Now is the time to double down on typhoid control and elimination by sustaining progress made through water, sanitation, and hygiene improvements and accelerating TCV introduction in high-burden locations.
format Online
Article
Text
id pubmed-10236514
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-102365142023-06-03 Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem Chen, Jessie Long, Jessica E Vannice, Kirsten Shewchuk, Tanya Kumar, Supriya Duncan Steele, A Zaidi, Anita K M Open Forum Infect Dis Charting the Course Supplement Typhoid fever is a significant global health problem that impacts people living in areas without access to clean water and sanitation. However, collaborative international partnerships and new research have improved both knowledge of the burden in countries with endemic disease and the tools for improved surveillance, including environmental surveillance. Two typhoid conjugate vaccines (TCVs) have achieved World Health Organization prequalification, with several more in the development pipeline. Despite hurdles posed by the coronavirus disease 2019 pandemic, multiple TCV efficacy trials have been conducted in high-burden countries, and data indicate that TCVs provide a high degree of protection from typhoid fever, are safe to use in young children, provide lasting protection, and have the potential to combat typhoid antimicrobial resistance. Now is the time to double down on typhoid control and elimination by sustaining progress made through water, sanitation, and hygiene improvements and accelerating TCV introduction in high-burden locations. Oxford University Press 2023-06-02 /pmc/articles/PMC10236514/ /pubmed/37274535 http://dx.doi.org/10.1093/ofid/ofad055 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Charting the Course Supplement
Chen, Jessie
Long, Jessica E
Vannice, Kirsten
Shewchuk, Tanya
Kumar, Supriya
Duncan Steele, A
Zaidi, Anita K M
Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem
title Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem
title_full Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem
title_fullStr Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem
title_full_unstemmed Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem
title_short Taking on Typhoid: Eliminating Typhoid Fever as a Global Health Problem
title_sort taking on typhoid: eliminating typhoid fever as a global health problem
topic Charting the Course Supplement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236514/
https://www.ncbi.nlm.nih.gov/pubmed/37274535
http://dx.doi.org/10.1093/ofid/ofad055
work_keys_str_mv AT chenjessie takingontyphoideliminatingtyphoidfeverasaglobalhealthproblem
AT longjessicae takingontyphoideliminatingtyphoidfeverasaglobalhealthproblem
AT vannicekirsten takingontyphoideliminatingtyphoidfeverasaglobalhealthproblem
AT shewchuktanya takingontyphoideliminatingtyphoidfeverasaglobalhealthproblem
AT kumarsupriya takingontyphoideliminatingtyphoidfeverasaglobalhealthproblem
AT duncansteelea takingontyphoideliminatingtyphoidfeverasaglobalhealthproblem
AT zaidianitakm takingontyphoideliminatingtyphoidfeverasaglobalhealthproblem