STAT3 regulates 5‐Fu resistance in human colorectal cancer cells by promoting Mcl‐1–dependent cytoprotective autophagy

Chemoresistance to 5‐fluorouracil (5‐Fu)‐based chemotherapy is one of the primary reasons for the failure of colorectal cancer (CRC) management. STAT3 can mediate tumor drug resistance through a variety of diverse mechanisms. Nonetheless, the underlying mechanisms of STAT3‐induced 5‐Fu resistance in...

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Detalles Bibliográficos
Autores principales: Yue, Yuanyi, Zhang, Qiang, Wang, Xueqing, Sun, Zhengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236628/
https://www.ncbi.nlm.nih.gov/pubmed/36788743
http://dx.doi.org/10.1111/cas.15761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236628/
https://www.ncbi.nlm.nih.gov/pubmed/36788743
http://dx.doi.org/10.1111/cas.15761

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