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Interactions between driver genes shape the signaling pathway landscape and direct hepatocellular carcinoma therapy

Hepatocellular carcinoma (HCC) is one of the most lethal malignancies, whose initiation and development are driven by alterations in driver genes. In this study, we identified four driver genes (TP53, PTEN, CTNNB1, and KRAS) that show a high frequency of somatic mutations or copy number variations (...

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Detalles Bibliográficos
Autores principales:	Shen, Yiqing, Zheng, Xiaohu, Qian, Yeben, Liu, Mantian, Nian, Zhigang, Cui, Quanwei, Zhou, Yonggang, Fu, Binqing, Sun, Rui, Tian, Zhigang, Wei, Haiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236629/ https://www.ncbi.nlm.nih.gov/pubmed/36919759 http://dx.doi.org/10.1111/cas.15788

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