PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo

BACKGROUND: Pulmonary fibrosis is a major category of end-stage changes in lung diseases, characterized by lung epithelial cell damage, proliferation of fibroblasts, and accumulation of extracellular matrix. Peroxiredoxin 1 (PRDX1), a member of the peroxiredoxin protein family, participates in the r...

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Detalles Bibliográficos
Autores principales: Sun, Hu-Nan, Ren, Chen-Xi, Lee, Dong Hun, Wang, Wei-Hao, Guo, Xiao-Yu, Hao, Ying-Ying, Wang, Xiao-Ming, Zhang, Hui-Na, Xiao, Wan-Qiu, Li, Nan, Cong, Jie, Han, Ying-Hao, Kwon, Taeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236698/
https://www.ncbi.nlm.nih.gov/pubmed/37268886
http://dx.doi.org/10.1186/s11658-023-00460-x

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