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A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with few effective therapeutic options. Recently, drug repositioning, which involves identifying novel therapeutic potentials for existing drugs, has been popularized as a new approach for the development of novel thera...
Autores principales: | Imakura, Takeshi, Sato, Seidai, Koyama, Kazuya, Ogawa, Hirohisa, Niimura, Takahiro, Murakami, Kojin, Yamashita, Yuya, Haji, Keiko, Naito, Nobuhito, Kagawa, Kozo, Kawano, Hiroshi, Zamami, Yoshito, Ishizawa, Keisuke, Nishioka, Yasuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236721/ https://www.ncbi.nlm.nih.gov/pubmed/37269004 http://dx.doi.org/10.1186/s12931-023-02446-x |
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