Microglia-derived TNF-α contributes to RVLM neuronal mitochondrial dysfunction via blocking the AMPK–Sirt3 pathway in stress-induced hypertension

BACKGROUND: Neuroinflammation in the rostral ventrolateral medulla (RVLM) has been associated with the pathogenesis of stress-induced hypertension (SIH). Neuronal mitochondrial dysfunction is involved in many pathological and physiological processes. However, the impact of neuroinflammation on neuro...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Linping, Liu, Tianfeng, Wang, Xueping, Tong, Lei, Chen, Gaojun, Zhou, Shumin, Zhang, Haili, Liu, Haisheng, Lu, Wen, Wang, Guohua, Zhang, Shuai, Du, Dongshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236846/
https://www.ncbi.nlm.nih.gov/pubmed/37264405
http://dx.doi.org/10.1186/s12974-023-02818-6

Ejemplares similares

Ejemplares similares