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Deep learning based detection of monkeypox virus using skin lesion images

As we set into the second half of 2022, the world is still recovering from the two-year COVID-19 pandemic. However, over the past three months, the outbreak of the Monkeypox Virus (MPV) has led to fifty-two thousand confirmed cases and over one hundred deaths. This caused the World Health Organisati...

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Autores principales: Nayak, Tushar, Chadaga, Krishnaraj, Sampathila, Niranjana, Mayrose, Hilda, Gokulkrishnan, Nitila, Bairy G, Muralidhar, Prabhu, Srikanth, S, Swathi K., Umakanth, Shashikiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236906/
https://www.ncbi.nlm.nih.gov/pubmed/37293134
http://dx.doi.org/10.1016/j.medntd.2023.100243
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author Nayak, Tushar
Chadaga, Krishnaraj
Sampathila, Niranjana
Mayrose, Hilda
Gokulkrishnan, Nitila
Bairy G, Muralidhar
Prabhu, Srikanth
S, Swathi K.
Umakanth, Shashikiran
author_facet Nayak, Tushar
Chadaga, Krishnaraj
Sampathila, Niranjana
Mayrose, Hilda
Gokulkrishnan, Nitila
Bairy G, Muralidhar
Prabhu, Srikanth
S, Swathi K.
Umakanth, Shashikiran
author_sort Nayak, Tushar
collection PubMed
description As we set into the second half of 2022, the world is still recovering from the two-year COVID-19 pandemic. However, over the past three months, the outbreak of the Monkeypox Virus (MPV) has led to fifty-two thousand confirmed cases and over one hundred deaths. This caused the World Health Organisation to declare the outbreak a Public Health Emergency of International Concern (PHEIC). If this outbreak worsens, we could be looking at the Monkeypox virus causing the next global pandemic. As Monkeypox affects the human skin, the symptoms can be captured with regular imaging. Large samples of these images can be used as a training dataset for machine learning-based detection tools. Using a regular camera to capture the skin image of the infected person and running it against computer vision models is beneficial. In this research, we use deep learning to diagnose monkeypox from skin lesion images. Using a publicly available dataset, we tested the dataset on five pre-trained deep neural networks: GoogLeNet, Places365-GoogLeNet, SqueezeNet, AlexNet and ResNet-18. Hyperparameter was done to choose the best parameters. Performance metrics such as accuracy, precision, recall, f1-score and AUC were considered. Among the above models, ResNet18 was able to obtain the highest accuracy of 99.49%. The modified models obtained validation accuracies above 95%. The results prove that deep learning models such as the proposed model based on ResNet-18 can be deployed and can be crucial in battling the monkeypox virus. Since the used networks are optimized for efficiency, they can be used on performance limited devices such as smartphones with cameras. The addition of explainable artificial intelligence techniques LIME and GradCAM enables visual interpretation of the prediction made, helping health professionals using the model.
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spelling pubmed-102369062023-06-02 Deep learning based detection of monkeypox virus using skin lesion images Nayak, Tushar Chadaga, Krishnaraj Sampathila, Niranjana Mayrose, Hilda Gokulkrishnan, Nitila Bairy G, Muralidhar Prabhu, Srikanth S, Swathi K. Umakanth, Shashikiran Med Nov Technol Devices Article As we set into the second half of 2022, the world is still recovering from the two-year COVID-19 pandemic. However, over the past three months, the outbreak of the Monkeypox Virus (MPV) has led to fifty-two thousand confirmed cases and over one hundred deaths. This caused the World Health Organisation to declare the outbreak a Public Health Emergency of International Concern (PHEIC). If this outbreak worsens, we could be looking at the Monkeypox virus causing the next global pandemic. As Monkeypox affects the human skin, the symptoms can be captured with regular imaging. Large samples of these images can be used as a training dataset for machine learning-based detection tools. Using a regular camera to capture the skin image of the infected person and running it against computer vision models is beneficial. In this research, we use deep learning to diagnose monkeypox from skin lesion images. Using a publicly available dataset, we tested the dataset on five pre-trained deep neural networks: GoogLeNet, Places365-GoogLeNet, SqueezeNet, AlexNet and ResNet-18. Hyperparameter was done to choose the best parameters. Performance metrics such as accuracy, precision, recall, f1-score and AUC were considered. Among the above models, ResNet18 was able to obtain the highest accuracy of 99.49%. The modified models obtained validation accuracies above 95%. The results prove that deep learning models such as the proposed model based on ResNet-18 can be deployed and can be crucial in battling the monkeypox virus. Since the used networks are optimized for efficiency, they can be used on performance limited devices such as smartphones with cameras. The addition of explainable artificial intelligence techniques LIME and GradCAM enables visual interpretation of the prediction made, helping health professionals using the model. The Authors. Published by Elsevier B.V. 2023-06 2023-06-02 /pmc/articles/PMC10236906/ /pubmed/37293134 http://dx.doi.org/10.1016/j.medntd.2023.100243 Text en © 2023 The Authors Elsevier has created a Monkeypox Information Center (https://www.elsevier.com/connect/monkeypox-information-center) in response to the declared public health emergency of international concern, with free information in English on the monkeypox virus. The Monkeypox Information Center is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its monkeypox related research that is available on the Monkeypox Information Center - including this research content - immediately available in publicly funded repositories, with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the Monkeypox Information Center remains active.
spellingShingle Article
Nayak, Tushar
Chadaga, Krishnaraj
Sampathila, Niranjana
Mayrose, Hilda
Gokulkrishnan, Nitila
Bairy G, Muralidhar
Prabhu, Srikanth
S, Swathi K.
Umakanth, Shashikiran
Deep learning based detection of monkeypox virus using skin lesion images
title Deep learning based detection of monkeypox virus using skin lesion images
title_full Deep learning based detection of monkeypox virus using skin lesion images
title_fullStr Deep learning based detection of monkeypox virus using skin lesion images
title_full_unstemmed Deep learning based detection of monkeypox virus using skin lesion images
title_short Deep learning based detection of monkeypox virus using skin lesion images
title_sort deep learning based detection of monkeypox virus using skin lesion images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236906/
https://www.ncbi.nlm.nih.gov/pubmed/37293134
http://dx.doi.org/10.1016/j.medntd.2023.100243
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