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Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method

Fluorobenzoic acids (FBAs) are used as chemical tracers in enhanced oil recovery and reduction in their limit of detection is a crucial issue. GC-MS is a versatile tool to detect and quantify FBAs at very low limits of concentration, but they require esterification prior to analysis by GC-MS. The pr...

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Detalles Bibliográficos
Autores principales: Kumar, Anuj, Singh, Satish Kumar, Sharma, Chhaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236933/
https://www.ncbi.nlm.nih.gov/pubmed/37274403
http://dx.doi.org/10.1039/d3ra02005c
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author Kumar, Anuj
Singh, Satish Kumar
Sharma, Chhaya
author_facet Kumar, Anuj
Singh, Satish Kumar
Sharma, Chhaya
author_sort Kumar, Anuj
collection PubMed
description Fluorobenzoic acids (FBAs) are used as chemical tracers in enhanced oil recovery and reduction in their limit of detection is a crucial issue. GC-MS is a versatile tool to detect and quantify FBAs at very low limits of concentration, but they require esterification prior to analysis by GC-MS. The present article presents a study of the catalytic methyl esterification of fluorinated aromatic carboxylic acids (FBAs) using methanol as methyl source and UiO-66-NH(2) as a heterogeneous catalyst. The reaction time was reduced to 10 hours which is a 58% reduction in time over the traditional BF(3)·MeOH complex as derivatizing agent. The yield of the esterification reaction was evaluated with respect to the BF(3)–MeOH complex and determined by GC-EI-MS. The catalytic procedure was optimized by the Taguchi model with a 99.99% fit. Good catalytic performance was observed for 23 different isomers of fluorinated aromatic acids showing a relative conversion yield of up to 169.86%, which reduced the detection limit of FBAs up to 2.60 ng mL(−1).
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spelling pubmed-102369332023-06-03 Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method Kumar, Anuj Singh, Satish Kumar Sharma, Chhaya RSC Adv Chemistry Fluorobenzoic acids (FBAs) are used as chemical tracers in enhanced oil recovery and reduction in their limit of detection is a crucial issue. GC-MS is a versatile tool to detect and quantify FBAs at very low limits of concentration, but they require esterification prior to analysis by GC-MS. The present article presents a study of the catalytic methyl esterification of fluorinated aromatic carboxylic acids (FBAs) using methanol as methyl source and UiO-66-NH(2) as a heterogeneous catalyst. The reaction time was reduced to 10 hours which is a 58% reduction in time over the traditional BF(3)·MeOH complex as derivatizing agent. The yield of the esterification reaction was evaluated with respect to the BF(3)–MeOH complex and determined by GC-EI-MS. The catalytic procedure was optimized by the Taguchi model with a 99.99% fit. Good catalytic performance was observed for 23 different isomers of fluorinated aromatic acids showing a relative conversion yield of up to 169.86%, which reduced the detection limit of FBAs up to 2.60 ng mL(−1). The Royal Society of Chemistry 2023-06-02 /pmc/articles/PMC10236933/ /pubmed/37274403 http://dx.doi.org/10.1039/d3ra02005c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Kumar, Anuj
Singh, Satish Kumar
Sharma, Chhaya
Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method
title Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method
title_full Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method
title_fullStr Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method
title_full_unstemmed Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method
title_short Esterification of fluorinated aromatic carboxylic acids with methanol by using UiO-66-NH(2) as a heterogeneous catalyst and process optimization by the Taguchi method
title_sort esterification of fluorinated aromatic carboxylic acids with methanol by using uio-66-nh(2) as a heterogeneous catalyst and process optimization by the taguchi method
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236933/
https://www.ncbi.nlm.nih.gov/pubmed/37274403
http://dx.doi.org/10.1039/d3ra02005c
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