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Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis

Neutrophil infiltration is a hallmark of periodontitis, a prevalent oral inflammatory condition in which Th17-driven mucosal inflammation leads to destruction of tooth-supporting bone. Herein, we document that neutrophil extracellular traps (NETs) are early triggers of pathogenic inflammation in per...

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Detalles Bibliográficos
Autores principales: Kim, Tae Sung, Silva, Lakmali M., Theofilou, Vasileios Ionas, Greenwell-Wild, Teresa, Li, Lu, Williams, Drake Winslow, Ikeuchi, Tomoko, Brenchley, Laurie, Bugge, Thomas H., Diaz, Patricia I., Kaplan, Mariana J., Carmona-Rivera, Carmelo, Moutsopoulos, Niki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236943/
https://www.ncbi.nlm.nih.gov/pubmed/37261457
http://dx.doi.org/10.1084/jem.20221751