Amino acid-mPEGs: Promising excipients to stabilize human growth hormone against aggregation

OBJECTIVE(S): Today, the non-covalent PEGylation methods of protein pharmaceuticals attract more attention and possess several advantages over the covalent approach. In the present study, Amino Acid-mPEGs (aa-mPEGs) were synthesized, and the human Growth Hormone (hGH) stability profile was assessed...

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Detalles Bibliográficos
Autores principales: Vakili, Somayeh, Chamani, JamshidKhan, Amiri-Tehranizadeh, Zeinab, Hosseinzadeh, Hossein, Mosaffa, Fatemeh, Khatami, Seyed-Mola, Khameneh, Bahman, Saberi, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237159/
https://www.ncbi.nlm.nih.gov/pubmed/37275756
http://dx.doi.org/10.22038/IJBMS.2023.67557.14804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237159/
https://www.ncbi.nlm.nih.gov/pubmed/37275756
http://dx.doi.org/10.22038/IJBMS.2023.67557.14804

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