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A whole‐genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors

The natural compound Artemisinin is the most widely used antimalarial drug worldwide. Based on its cytotoxicity, it is also used for anticancer therapy. Artemisinin and its derivates are endoperoxides that damage proteins in eukaryotic cells; their definite mechanism of action and host cell targets,...

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Detalles Bibliográficos
Autores principales: Taubenschmid‐Stowers, Jasmin, Orthofer, Michael, Laemmerer, Anna, Krauditsch, Christian, Rózsová, Marianna, Studer, Christian, Lötsch, Daniela, Gojo, Johannes, Gabler, Lisa, Dyczynski, Matheus, Efferth, Thomas, Hagelkruys, Astrid, Widhalm, Georg, Peyrl, Andreas, Spiegl‐Kreinecker, Sabine, Hoepfner, Dominic, Bian, Shan, Berger, Walter, Knoblich, Juergen A, Elling, Ulrich, Horn, Moritz, Penninger, Josef M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237280/
https://www.ncbi.nlm.nih.gov/pubmed/36740985
http://dx.doi.org/10.15252/emmm.202216959