Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro

BACKGROUND: Neutrophils, key players of the immune system, also promote tumor development through the formation of neutrophil extracellular traps (NETs) in a process called NETosis. NETs are extracellular networks of DNA, histones and cytoplasmic and granular proteins (calprotectin, myeloperoxidase,...

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Detalles Bibliográficos
Autores principales: Herranz, Raquel, Oto, Julia, Hueso, Marta, Plana, Emma, Cana, Fernando, Castaño, María, Cordón, Lourdes, Ramos-Soler, David, Bonanad, Santiago, Vera-Donoso, César D., Martínez-Sarmiento, Manuel, Medina, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237292/
https://www.ncbi.nlm.nih.gov/pubmed/37275882
http://dx.doi.org/10.3389/fimmu.2023.1171065

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