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Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated T-cell pediatric acute liver failure

A distinct phenotype of pediatric acute liver failure (PALF) has been identified, labeled activated T-cell hepatitis. These patients, previously included within the indeterminate group, have evidence of systemic immune activation and liver biopsy specimens with dense infiltration of CD8+ T-cells. We...

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Detalles Bibliográficos
Autores principales:	Chapin, Catherine A., Burn, Thomas M., Diamond, Tamir, Loomes, Kathleen M., Alonso, Estella M., Behrens, Edward M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237500/ https://www.ncbi.nlm.nih.gov/pubmed/37267251 http://dx.doi.org/10.1371/journal.pone.0286394

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