Cargando…

Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated T-cell pediatric acute liver failure

A distinct phenotype of pediatric acute liver failure (PALF) has been identified, labeled activated T-cell hepatitis. These patients, previously included within the indeterminate group, have evidence of systemic immune activation and liver biopsy specimens with dense infiltration of CD8+ T-cells. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chapin, Catherine A., Burn, Thomas M., Diamond, Tamir, Loomes, Kathleen M., Alonso, Estella M., Behrens, Edward M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10237500/ https://www.ncbi.nlm.nih.gov/pubmed/37267251 http://dx.doi.org/10.1371/journal.pone.0286394

Ejemplares similares

Transcriptional Analysis of Liver Tissue Identifies Distinct Phenotypes of Indeterminate Pediatric Acute Liver Failure
por: Chapin, Catherine A, et al.
Publicado: (2021)

Disruption of IL-33 Signaling Limits Early CD8+ T Cell Effector Function Leading to Exhaustion in Murine Hemophagocytic Lymphohistiocytosis
por: Rood, Julia E., et al.
Publicado: (2018)

Rapid Effector Function in CD8(+) Memory T Cells
por: Lalvani, Ajit, et al.
Publicado: (1997)

Transcriptional and Epigenetic Regulation of Effector and Memory CD8 T Cell Differentiation
por: Chen, Yao, et al.
Publicado: (2018)

Decreased effector memory CD45RA(+ )CD62L(- )CD8(+ )T cells and increased central memory CD45RA(- )CD62L(+ )CD8(+ )T cells in peripheral blood of rheumatoid arthritis patients
por: Maldonado, Anastacia, et al.
Publicado: (2003)

Chlamydia pneumoniae-Induced IFN-Gamma Responses in Peripheral Blood Mononuclear Cells Increase Numbers of CD4+ but Not CD8+ T Effector Memory Cells
por: Smith-Norowitz, Tamar A, et al.
Publicado: (2021)

Migratory Properties of Naive, Effector, and Memory Cd8(+) T Cells
por: Weninger, Wolfgang, et al.
Publicado: (2001)

Impact of Inflammatory Cytokines on Effector and Memory CD8+ T Cells
por: Kim, Marie T., et al.
Publicado: (2014)

EFFECTOR CD8 T CELLS DEDIFFERENTIATE INTO LONG-LIVED MEMORY CELLS
por: Youngblood, Ben, et al.
Publicado: (2017)

WASp Is Essential for Effector-to-Memory conversion and for Maintenance of CD8(+)T Cell Memory
por: Liu, Qiao, et al.
Publicado: (2019)

Tumor-specific CD4(+) T cells maintain effector and memory tumor-specific CD8(+) T cells
por: Church, Sarah E, et al.
Publicado: (2014)

CD4(+) T effector memory cell responses in Chlamydia pneumoniae‐stimulated peripheral blood mononuclear cells in nonasthmatic subjects
por: Smith‐Norowitz, Tamar A., et al.
Publicado: (2022)

Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection
por: Opata, Michael M., et al.
Publicado: (2018)

miRNA Profiling of Naïve, Effector and Memory CD8 T Cells
por: Wu, Haoquan, et al.
Publicado: (2007)

Phenotypic and Functional Separation of Memory and Effector Human CD8(+) T Cells
por: Hamann, Dörte, et al.
Publicado: (1997)

Autophagy is essential for effector CD8 T cell survival and memory formation
por: Xu, Xiaojin, et al.
Publicado: (2014)

Sirtuin 5 is Dispensable for CD8(+) T Cell Effector and Memory Differentiation
por: Duan, Qianqian, et al.
Publicado: (2021)

GOT1 regulates CD8(+) effector and memory T cell generation
por: Xu, Wei, et al.
Publicado: (2023)

Differentiation of Memory CD8 T Cells Unravel Gene Expression Pattern Common to Effector and Memory Precursors
por: Neitzke-Montinelli, Vanessa, et al.
Publicado: (2022)

Wnt signaling arrests effector T cell differentiation and generates CD8(+) memory stem cells
por: Gattinoni, Luca, et al.
Publicado: (2009)

Themis controls T cell activation, effector functions, and metabolism of peripheral CD8(+) T cells
por: Gautam, Namrata, et al.
Publicado: (2023)

The smallest unit: effector and memory CD8(+) T cell differentiation on the single cell level
por: Buchholz, Veit R., et al.
Publicado: (2013)

Early CD8 T-cell memory precursors and terminal effectors exhibit equipotent in vivo degranulation
por: Yuzefpolskiy, Yevgeniy, et al.
Publicado: (2015)

Peripheral Tissue Homing Receptor Control of Naïve, Effector, and Memory CD8 T Cell Localization in Lymphoid and Non-Lymphoid Tissues
por: Brinkman, C. Colin, et al.
Publicado: (2013)

Immediate Cytotoxicity But Not Degranulation Distinguishes Effector and Memory Subsets of CD8(+) T Cells
por: Wolint, Petra, et al.
Publicado: (2004)

Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune Response
por: Reiser, John, et al.
Publicado: (2016)

Shared acute phase traits in effector and memory human CD8 T cells()
por: Fuertes Marraco, Silvia A., et al.
Publicado: (2021)

Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung
por: Morabito, Kaitlyn M., et al.
Publicado: (2016)

Effector and Central Memory Poly-Functional CD4(+) and CD8(+) T Cells are Boosted upon ZOSTAVAX(®) Vaccination
por: Sei, Janet J., et al.
Publicado: (2015)

Memory CD8(+) T cells upregulate glycolysis and effector functions under limiting oxygen conditions
por: Beumer‐Chuwonpad, Ammarina, et al.
Publicado: (2022)

Analysis of Mitochondrial Function in Antigen Specific na ve, Effector and MEmory CD8 + T Cells
por: Grayson, Jason M., et al.
Publicado: (2001)

Antigen-specific decidual CD8(+) T cells include distinct effector memory and tissue-resident memory cells
por: Mahajan, Shweta, et al.
Publicado: (2023)

Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis
por: Abdelsamed, Hossam A., et al.
Publicado: (2017)

B cell adaptor for PI3-kinase (BCAP) modulates CD8(+) effector and memory T cell differentiation
por: Singh, Mark D., et al.
Publicado: (2018)

Protective Effector Memory CD4 T Cells Depend on ICOS for Survival
por: Moore, Tamson V., et al.
Publicado: (2011)

Dicer Regulates the Balance of Short-Lived Effector and Long-Lived Memory CD8 T Cell Lineages
por: Baumann, Florian M., et al.
Publicado: (2016)

Effector Memory CD8(+) and CD4(+) T Cell Immunity Associated with Metabolic Syndrome in Obese Children
por: Yang, Da-Hee, et al.
Publicado: (2021)

Mitochondrial Dysfunction in CD4+ T Effector Memory RA+ Cells
por: Strickland, Marie, et al.
Publicado: (2023)

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
por: Sarkar, Surojit, et al.
Publicado: (2008)

Role of functional avidity in HIV-specific memory CD8 T cell effector functions
por: Lemon, Tiffany, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_8fui3tohuij88cotnl39pvheic