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Deafness‐Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment

The ankle‐link complex (ALC) consists of USH2A, WHRN, PDZD7, and ADGRV1 and plays an important role in hair cell development. At present, its architectural organization and signaling role remain unclear. By establishing Adgrv1 Y6236fsX1 mutant mice as a model of the deafness‐associated human Y6244fs...

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Detalles Bibliográficos
Autores principales:	Guan, Ying, Du, Hai‐Bo, Yang, Zhao, Wang, Yu‐Zhu, Ren, Rui, Liu, Wen‐Wen, Zhang, Chao, Zhang, Jia‐Hai, An, Wen‐Tao, Li, Na‐Na, Zeng, Xiao‐Xue, Li, Jie, Sun, Yi‐Xiao, Wang, Yan‐Fei, Yang, Fan, Yang, Jun, Xiong, Wei, Yu, Xiao, Chai, Ren‐Jie, Tu, Xiao‐Ming, Sun, Jin‐Peng, Xu, Zhi‐Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238197/ https://www.ncbi.nlm.nih.gov/pubmed/37066759 http://dx.doi.org/10.1002/advs.202205993

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