De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity

Oncogenic stress induces DNA damage repair (DDR) that permits escape from mitotic catastrophe and allows early precursor lesions during the evolution of cancer. SAMHD1, a dNTPase protecting cells from viral infections, has been recently found to participate in DNA damage repair process. However, its...

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Detalles Bibliográficos
Autores principales: Liu, Jingwei, Zhou, Tingting, Dong, Xiang, Guo, Qiqiang, Zheng, Lixia, Wang, Xiaoxun, Zhang, Naijin, Li, Danni, Ren, Ling, Yi, Fei, Zhang, Ying, Li, Ziwei, Wang, Xiwen, Deng, Chengsi, Li, Chunlu, Xu, Hongde, Guan, Yi, Li, Xiaoman, Yu, Yang, Guo, Wendong, Wang, Zhuo, Jiang, Bo, Wu, Xuan, Bai, Ning, Feng, Yanling, Ma, Mengtao, Kong, Qingquan, Wei, Jiayi, Wang, Zhenshuang, Li, Hao, Lu, Songming, Cao, Liangzi, Xiao, Yutong, Song, Xiaoyu, Wang, Zhenning, Xing, Chengzhong, Cao, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238270/
https://www.ncbi.nlm.nih.gov/pubmed/37081042
http://dx.doi.org/10.1038/s41388-023-02667-w

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