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Changes within the P681 residue of spike dictate cell fusion and syncytia formation of Delta and Omicron variants of SARS-CoV-2 with no effects on neutralization or infectivity

The rapid spread and dominance of the Omicron SARS-CoV-2 lineages have posed severe health challenges worldwide. While extensive research on the role of the Receptor Binding Domain (RBD) in promoting viral infectivity and vaccine sensitivity has been well documented, the functional significance of t...

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Detalles Bibliográficos
Autores principales: Kuzmina, Alona, Korovin, Dina, Cohen lass, Ido, Atari, Nofar, Ottolenghi, Aner, Hu, Pan, Mandelboim, Michal, Rosental, Benyamin, Rosenberg, Elli, Diaz-Griffero, Felipe, Taube, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238279/
https://www.ncbi.nlm.nih.gov/pubmed/37292300
http://dx.doi.org/10.1016/j.heliyon.2023.e16750