Cargando…

Stage III deficient mismatch repair colon patients get greater benefit from earlier starting oxaliplatin-based chemotherapy regimen

We evaluate the prognostic value of chemotherapy and other prognostic factors on overall survival among colon patients with deficient mismatch repair (dMMR), and determine the optimum time to start chemotherapy after surgery. Data of 306 colon cancer patients with dMMR who received radical surgery w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhan, Yixiang, Ni, Kemin, Liu, Zhaoce, xin, Ran, Han, Qiurong, Ping, Hangyu, Liu, Yaohong, Zhao, Xuanzhu, Wang, Wanting, Yan, Suying, Sun, Jing, Zhang, Qinghuai, Wang, Guihua, Zhang, Zili, Zhang, Xipeng, Hu, Xia, Li, Guoxun, Zhang, Chunze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238399/ https://www.ncbi.nlm.nih.gov/pubmed/37268749 http://dx.doi.org/10.1038/s41598-023-33153-8

Ejemplares similares

Effects of deficient mismatch repair on the prognosis of patients with stage II and stage III colon cancer during different postoperative periods
por: Zhang, Chunze, et al.
Publicado: (2022)

Survival outcomes in locally advanced dMMR rectal cancer: surgery plus adjunctive treatment vs. surgery alone
por: Ni, Kemin, et al.
Publicado: (2023)

The stool syndecan2 methylation test is more robust than blood tests for methylated septin9, CEA, CA19-9 and CA724: a diagnostic test for the early detection of colorectal neoplasms
por: Zhan, Yixiang, et al.
Publicado: (2023)

Circulating Methylated SEPT9 DNA Analyses to Predict Recurrence Risk and Adjuvant Chemotherapy Benefit in Stage II to III Colorectal Cancer
por: Yuan, Zhen, et al.
Publicado: (2022)

Young Patients With Colorectal Cancer Have Higher Early Mortality but Better Long-Term Survival
por: Wang, Shuyuan, et al.
Publicado: (2022)

Modifiable lifestyle factors have a larger contribution to colorectal neoplasms than family history
por: Wang, Shuyuan, et al.
Publicado: (2022)

Colonoscopy compliance and diagnostic yield in a large population-based colorectal cancer screening programme
por: Zhao, Xinzhu, et al.
Publicado: (2023)

Clinicopathological and prognostic value of SIRT6 in patients with solid tumors: a meta-analysis and TCGA data review
por: Wu, Xiaojing, et al.
Publicado: (2022)

Case report: Camrelizumab associated with central retinal vein occlusion
por: Zhan, Yixiang, et al.
Publicado: (2022)

The accuracy of the FIT in detecting advanced neoplasm is highest in young people aged 40 to 49 years: an analysis based on sex and age
por: Zhao, Kailong, et al.
Publicado: (2023)

The comparison of risk factors for colorectal neoplasms at different anatomical sites
por: Wang, Huaqing, et al.
Publicado: (2023)

Zanthoxylum bungeanum seed oil inhibits tumorigenesis of human melanoma A375 by regulating CDC25A/CyclinB1/CDK1 signaling pathways in vitro and in vivo
por: Wang, Wanting, et al.
Publicado: (2023)

A risk scoring system for advanced colorectal neoplasia in high-risk participants to improve current colorectal cancer screening in Tianjin, China
por: Yuan, Zhen, et al.
Publicado: (2022)

Earlier-Season Vegetation Has Greater Temperature Sensitivity of Spring Phenology in Northern Hemisphere
por: Shen, Miaogen, et al.
Publicado: (2014)

An earlier time of scan is associated with greater threat-related amygdala reactivity
por: Baranger, David A. A., et al.
Publicado: (2017)

Greater Adolescent Cognitive Ability Linked to Lower Risk of Earlier Mortality
por: Gruenewald, Tara, et al.
Publicado: (2021)

Greater Adolescent Cognitive Ability Linked to Lower Risk of Earlier Mortality
por: Gruenewald, Tara, et al.
Publicado: (2021)

Higher titer hepatitis B core antibody predicts a higher risk of liver metastases and worse survival in patients with colorectal cancer
por: Li, Ziyao, et al.
Publicado: (2021)

Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in C. elegans
por: Gaffney, Christopher J., et al.
Publicado: (2018)

Prenatal cadmium exposure does not induce greater incidence or earlier onset of autoimmunity in the offspring
por: McCall, Jamie L., et al.
Publicado: (2021)

Greater chronic morbidity is associated with greater fatigue in six countries: A case of evolutionary mismatch?
por: Schrock, Joshua M, et al.
Publicado: (2022)

Drug-induced liver injury in COVID-19 treatment: Incidence, mechanisms and clinical management
por: Li, Xichuan, et al.
Publicado: (2022)

Earlier Onset and Greater Severity of Disordered Mineral Metabolism in Diabetic Patients With Chronic Kidney Disease
por: Wahl, Patricia, et al.
Publicado: (2012)

Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells
por: Nehmé, A, et al.
Publicado: (1999)

FTO promotes colorectal cancer progression and chemotherapy resistance via demethylating G6PD/PARP1
por: Wang, Jiyan, et al.
Publicado: (2022)

Prognostic factors for transarterial chemoembolization combined with sustained oxaliplatin-based hepatic arterial infusion chemotherapy of colorectal cancer liver metastasis
por: Zhang, Hangyu, et al.
Publicado: (2017)

Pre-attentive Mismatch Response and Involuntary Attention Switching to a Deviance in an Earlier-Than-Usual Auditory Stimulus: An ERP Study
por: Ungan, Pekcan, et al.
Publicado: (2019)

Faster‐acting insulin aspart: earlier onset of appearance and greater early pharmacokinetic and pharmacodynamic effects than insulin aspart
por: Heise, T., et al.
Publicado: (2015)

The Earlier Years
Publicado: (2001)

Common genetic variant rs3802842 in 11q23 contributes to colorectal cancer risk in Chinese population
por: Zhang, Chunze, et al.
Publicado: (2017)

Greater Impact of Living Donation Than HLA Mismatching in Short-Term Renal Allograft Survival
por: Ribeiro, Bárbara, et al.
Publicado: (2023)

Earlier snowmelt and warming lead to earlier but not necessarily more plant growth
por: Livensperger, Carolyn, et al.
Publicado: (2016)

Survival benefit of preoperative hepatic arterial infusion of oxaliplatin, fluorouracil, and leucovorin followed by hepatectomy for hepatocellular carcinoma
por: Hu, Zili, et al.
Publicado: (2023)

SMAD7 rs4939827 variant contributes to colorectal cancer risk in Chinese population
por: Zhang, Chunze, et al.
Publicado: (2017)

Syphilis in Earlier Days
Publicado: (1941)

The Earlier Recognition of Cancer
por: Young, James
Publicado: (1926)

β-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1
por: Li, Xiaoqiang, et al.
Publicado: (2016)

Oxaliplatin plus irinotecan vs irinotecan as second-line treatment in pancreatic cancer patients: a randomized–controlled open-label Phase II study
por: Zhang, Hangyu, et al.
Publicado: (2023)

Earlier Initiation and Use of a Greater Number of Iron-Folic Acid Supplements during Pregnancy Prevents Early Neonatal Deaths in Nepal and Pakistan
por: Nisar, Yasir Bin, et al.
Publicado: (2014)

Paclitaxel/oxaliplatin/fluorouracil (TOF) regimen versus S-1/oxaliplatin (SOX) regimen for metastatic gastric cancer patients
por: Dai, Xichao, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ucf81vf37qd4l9qqbkb78q1gq4