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Transcriptomics, metabolomics, and in-silico drug predictions for liver damage in young and aged burn victims

Burn induces a systemic response affecting multiple organs, including the liver. Since the liver plays a critical role in metabolic, inflammatory, and immune events, a patient with impaired liver often exhibits poor outcomes. The mortality rate after burns in the elderly population is higher than in...

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Detalles Bibliográficos
Autores principales: Malachowska, Beata, Yang, Weng-Lang, Qualman, Andrea, Muro, Israel, Boe, Devin M., Lampe, Jed N., Kovacs, Elizabeth J., Idrovo, Juan-Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238406/
https://www.ncbi.nlm.nih.gov/pubmed/37268765
http://dx.doi.org/10.1038/s42003-023-04964-2