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Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany

To analyze growth patterns of children with CP between countries; to examine differences in growth; and to assess the fit of growth charts. Cross-sectional study in children with CP from 2 to 19 years old, 399 from Argentina and 400 from Germany. Growth measures were converted into z-scores and comp...

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Autores principales: Ruiz Brunner, Maria de las Mercedes, Cuestas, Eduardo, von Kries, Rüdiger, Brooks, Jordan, Wright, Charlotte, Heinen, Florian, Schroeder, Andreas Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238482/
https://www.ncbi.nlm.nih.gov/pubmed/37268651
http://dx.doi.org/10.1038/s41598-023-34634-6
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author Ruiz Brunner, Maria de las Mercedes
Cuestas, Eduardo
von Kries, Rüdiger
Brooks, Jordan
Wright, Charlotte
Heinen, Florian
Schroeder, Andreas Sebastian
author_facet Ruiz Brunner, Maria de las Mercedes
Cuestas, Eduardo
von Kries, Rüdiger
Brooks, Jordan
Wright, Charlotte
Heinen, Florian
Schroeder, Andreas Sebastian
author_sort Ruiz Brunner, Maria de las Mercedes
collection PubMed
description To analyze growth patterns of children with CP between countries; to examine differences in growth; and to assess the fit of growth charts. Cross-sectional study in children with CP from 2 to 19 years old, 399 from Argentina and 400 from Germany. Growth measures were converted into z-scores and compared to WHO reference and US CP growth charts. Generalized Linear Model was used to analyze the growth expressed as mean z-scores. 799 children. Mean age 9 years (± 4). Compared to the WHO reference, the decrease in Height z-scores (HAZ) with age in Argentina (− 0.144/year) was double that in Germany (− 0.073/year). For children in GMFCS IV–V, BMI z-scores (BMIZ) decreased with age (− 0.102/year). Using the US CP charts, both countries showed decreasing HAZ with age, in Argentina (− 0.066/year) and in Germany (− 0.032/year). BMIZ increased more among children with feeding tubes (0.062/year), similar in both countries. Argentinian children with oral feeding decrease their Weight z-score (WAZ) by − 0.553 compared to their peers. With WHO charts BMIZ presented an excellent fit for GMFCS I–III. HAZ presents a poor fit to growth references. BMIZ and WAZ presented a good fit to US CP Charts. Growth differences due to ethnicity also act in children with CP, and are related to motor impairment, age and feeding modality, possibly reflecting differences in environment or health care.
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spelling pubmed-102384822023-06-04 Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany Ruiz Brunner, Maria de las Mercedes Cuestas, Eduardo von Kries, Rüdiger Brooks, Jordan Wright, Charlotte Heinen, Florian Schroeder, Andreas Sebastian Sci Rep Article To analyze growth patterns of children with CP between countries; to examine differences in growth; and to assess the fit of growth charts. Cross-sectional study in children with CP from 2 to 19 years old, 399 from Argentina and 400 from Germany. Growth measures were converted into z-scores and compared to WHO reference and US CP growth charts. Generalized Linear Model was used to analyze the growth expressed as mean z-scores. 799 children. Mean age 9 years (± 4). Compared to the WHO reference, the decrease in Height z-scores (HAZ) with age in Argentina (− 0.144/year) was double that in Germany (− 0.073/year). For children in GMFCS IV–V, BMI z-scores (BMIZ) decreased with age (− 0.102/year). Using the US CP charts, both countries showed decreasing HAZ with age, in Argentina (− 0.066/year) and in Germany (− 0.032/year). BMIZ increased more among children with feeding tubes (0.062/year), similar in both countries. Argentinian children with oral feeding decrease their Weight z-score (WAZ) by − 0.553 compared to their peers. With WHO charts BMIZ presented an excellent fit for GMFCS I–III. HAZ presents a poor fit to growth references. BMIZ and WAZ presented a good fit to US CP Charts. Growth differences due to ethnicity also act in children with CP, and are related to motor impairment, age and feeding modality, possibly reflecting differences in environment or health care. Nature Publishing Group UK 2023-06-02 /pmc/articles/PMC10238482/ /pubmed/37268651 http://dx.doi.org/10.1038/s41598-023-34634-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ruiz Brunner, Maria de las Mercedes
Cuestas, Eduardo
von Kries, Rüdiger
Brooks, Jordan
Wright, Charlotte
Heinen, Florian
Schroeder, Andreas Sebastian
Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany
title Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany
title_full Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany
title_fullStr Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany
title_full_unstemmed Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany
title_short Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany
title_sort growth patterns in children and adolescents with cerebral palsy from argentina and germany
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238482/
https://www.ncbi.nlm.nih.gov/pubmed/37268651
http://dx.doi.org/10.1038/s41598-023-34634-6
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