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Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons
CHD8 encodes chromodomain helicase DNA-binding protein 8 and its mutation is a highly penetrant risk factor for autism spectrum disorder (ASD). CHD8 serves as a key transcriptional regulator on the basis of its chromatin-remodeling activity and thereby controls the proliferation and differentiation...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238509/ https://www.ncbi.nlm.nih.gov/pubmed/37268684 http://dx.doi.org/10.1038/s42003-023-04968-y |