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CUL4B orchestrates mesenchymal stem cell commitment by epigenetically repressing KLF4 and C/EBPδ

Dysregulated lineage commitment of mesenchymal stem cells (MSCs) contributes to impaired bone formation and an imbalance between adipogenesis and osteogenesis during skeletal aging and osteoporosis. The intrinsic cellular mechanism that regulates MSC commitment remains unclear. Here, we identified C...

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Detalles Bibliográficos
Autores principales:	Yu, Ruiqi, Han, Hong, Chu, Shuxian, Ding, Yijun, Jin, Shiqi, Wang, Yufeng, Jiang, Wei, Liu, Yuting, Zou, Yongxin, Wang, Molin, Liu, Qiao, Sun, Gongping, Jiang, Baichun, Gong, Yaoqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238510/ https://www.ncbi.nlm.nih.gov/pubmed/37268647 http://dx.doi.org/10.1038/s41413-023-00263-y

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