Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer

Dysregulation of cellular metabolism is a hallmark of breast cancer progression and is associated with metastasis and therapeutic resistance. Here, we show that the breast tumor suppressor gene SIM2 promotes mitochondrial oxidative phosphorylation (OXPHOS) using breast cancer cell line models. Mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Wall, Steven W., Sanchez, Lilia, Tuttle, Kelly Scribner, Pearson, Scott J., Soma, Shivatheja, Wyatt, Garhett L., Carter, Hannah N., Jenschke, Ramsey M., Tan, Lin, Martinez, Sara A., Lorenzi, Philip L., Gohil, Vishal M., Rijnkels, Monique, Porter, Weston W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238511/
https://www.ncbi.nlm.nih.gov/pubmed/37121978
http://dx.doi.org/10.1038/s12276-023-00996-0

Ejemplares similares

Ejemplares similares