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Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard

Adeno-associated viruses (AAVs) are non-enveloped ssDNA icosahedral T = 1 viruses used as vectors for clinical gene delivery. Currently, there are over 200 AAV-related clinical trials and six approved biologics on the market. As such new analytical methods are continually being developed to characte...

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Detalles Bibliográficos
Autores principales: Mietzsch, Mario, Liu, Weijing, Ma, Ke, Bennett, Antonette, Nelson, Austin R., Gliwa, Keely, Chipman, Paul, Fu, Xiaofeng, Bechler, Shane, McKenna, Robert, Viner, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238842/
https://www.ncbi.nlm.nih.gov/pubmed/37273903
http://dx.doi.org/10.1016/j.omtm.2023.05.002