KCNJ15 deficiency promotes drug resistance via affecting the function of lysosomes

The altered lysosomal function can induce drug redistribution which leads to drug resistance and poor prognosis for cancer patients. V-ATPase, an ATP-driven proton pump positioned at lysosomal surfaces, is responsible for maintaining the stability of lysosome. Herein, we reported that the potassium...

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Detalles Bibliográficos
Autores principales: Qiao, Xinbo, Zhang, Yixiao, Zhang, Zhan, Niu, Nan, Li, Haonan, Sun, Lisha, Ma, Qingtian, Bu, Jiawen, Liu, Jinchi, Chen, Guanglei, Xue, Jinqi, Yang, Yongliang, Liu, Caigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2023
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238847/
https://www.ncbi.nlm.nih.gov/pubmed/37274925
http://dx.doi.org/10.1016/j.ajps.2023.100814

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