Application of the patient-reported outcomes continual reassessment method to a phase I study of radiotherapy in endometrial cancer

This article considers the concept of designing Phase I clinical trials using both clinician- and patient-reported outcomes to adaptively allocate study participants to tolerable doses and determine the maximum tolerated dose (MTD) at the study conclusion. We describe an application of a Bayesian fo...

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Detalles Bibliográficos
Autores principales: Wages, Nolan A., Nelson, Bailey, Kharofa, Jordan, Meier, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238853/
https://www.ncbi.nlm.nih.gov/pubmed/36394530
http://dx.doi.org/10.1515/ijb-2022-0023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238853/
https://www.ncbi.nlm.nih.gov/pubmed/36394530
http://dx.doi.org/10.1515/ijb-2022-0023

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