Pulmonary primary meningioma: A report of two cases and review of the literature

INTRODUCTION: Primary pulmonary meningioma (PPM) is rare, mostly asymptomatic, and difficult to recognize preoperatively. In this report, we describe two new cases of PPM and provide an updated review of the literature to enhance our understanding of PPM. CASE PRESENTATION: The first patient was a 53-year-old woman with an asymptomatic solitary pulmonary nodule in the right lower lobe on chest computed tomography (CT). Wedge resection of the right lung was performed and histological features of benign PPM were pathologically confirmed, which was further supported by immunohistochemistry. The second patient was a 63-year-old man who had a left pulmonary nodule during routine physical examination. CT revealed a solid nodule in the outer basal segment of the left lower lobe. The patient underwent a wedge resection of the left lower lobe and mediastinal lymph node dissection. Postoperative pathology confirmed the presence of two tumors: one adenocarcinoma and one PPM. Both cases were confirmed to be benign PPM (grade I) by pathological examination, with histological subtypes of fibrous and psammomatous. CONCLUSIONS: Radiological imaging is crucial for the early detection of PPM, while pathological examination is necessary to confirm the diagnosis. Surgical treatment is recommended, and intraoperative frozen sections are essential for determining the extent of the operation.