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CD168(+) macrophages promote hepatocellular carcinoma tumor stemness and progression through TOP2A/β-catenin/YAP1 axis

Liver cancer stem-like cells (LCSCs) are the main cause of heterogeneity and poor prognosis in hepatocellular carcinoma (HCC). In this study, we aimed to explore the origin of LCSCs and the role of the TOP2A/β-catenin/YAP1 axis in tumor stemness and progression. Using single-cell RNA-seq analysis, w...

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Detalles Bibliográficos
Autores principales:	Zhao, Hai-Chao, Chen, Chang-Zhou, Tian, Yan-Zhang, Song, Huang-Qin, Wang, Xiao-Xiao, Li, Yan-Jun, He, Jie-Feng, Zhao, Hao-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10238939/ https://www.ncbi.nlm.nih.gov/pubmed/37275516 http://dx.doi.org/10.1016/j.isci.2023.106862

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