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Genetic deletion of skeletal muscle iPLA(2)γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism

Skeletal muscle is the major site of glucose utilization in mammals integrating serum glucose clearance with mitochondrial respiration. To mechanistically elucidate the roles of iPLA(2)γ in skeletal muscle mitochondria, we generated a skeletal muscle-specific calcium-independent phospholipase A(2)γ...

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Detalles Bibliográficos
Autores principales: Moon, Sung Ho, Dilthey, Beverly Gibson, Guan, Shaoping, Sims, Harold F., Pittman, Sara K., Keith, Amy L., Jenkins, Christopher M., Weihl, Conrad C., Gross, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239068/
https://www.ncbi.nlm.nih.gov/pubmed/37275531
http://dx.doi.org/10.1016/j.isci.2023.106895