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Genetic deletion of skeletal muscle iPLA(2)γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism
Skeletal muscle is the major site of glucose utilization in mammals integrating serum glucose clearance with mitochondrial respiration. To mechanistically elucidate the roles of iPLA(2)γ in skeletal muscle mitochondria, we generated a skeletal muscle-specific calcium-independent phospholipase A(2)γ...
Autores principales: | Moon, Sung Ho, Dilthey, Beverly Gibson, Guan, Shaoping, Sims, Harold F., Pittman, Sara K., Keith, Amy L., Jenkins, Christopher M., Weihl, Conrad C., Gross, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239068/ https://www.ncbi.nlm.nih.gov/pubmed/37275531 http://dx.doi.org/10.1016/j.isci.2023.106895 |
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