Synergistic apoptosis by combination of metformin and an O-GlcNAcylation inhibitor in colon cancer cells

BACKGROUND: Although autophagy is an important mediator of metformin antitumor activity, the role of metformin in the crosstalk between autophagy and apoptosis remains unclear. The aim was to confirm the anticancer effect by inducing apoptosis by co-treatment with metformin and OSMI-1, an inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Da Eun, Lee, Geun Yong, Lee, Hae Min, Choi, Soo Young, Lee, Su Jin, Kwon, Oh-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239094/
https://www.ncbi.nlm.nih.gov/pubmed/37268905
http://dx.doi.org/10.1186/s12935-023-02954-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239094/
https://www.ncbi.nlm.nih.gov/pubmed/37268905
http://dx.doi.org/10.1186/s12935-023-02954-2

Ejemplares similares