Cross-sectional analysis characterizing the use of rank preserving structural failure time in oncology studies: changes to hazard ratio and frequency of inappropriate use

BACKGROUND: Rank preserving structural failure time (RPSFT) is a statistical method to correct or adjust for crossover in clinical trials, by estimating the counterfactual effect on overall survival (OS) when control arm patients do not receive the interventional drug when their tumor progresses. We...

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Detalles Bibliográficos
Autores principales: Prasad, Vinay, Kim, Myung Sun, Haslam, Alyson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239129/
https://www.ncbi.nlm.nih.gov/pubmed/37270500
http://dx.doi.org/10.1186/s13063-023-07412-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239129/
https://www.ncbi.nlm.nih.gov/pubmed/37270500
http://dx.doi.org/10.1186/s13063-023-07412-y

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