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APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia

BACKGROUND: White matter hyperintensities, a neuroimaging marker of small-vessel cerebrovascular disease and apolipoprotein ε4 (APOE4) allele, are important dementia risk factors. However, APOE4 as a key effect modifier in the relationship between white matter hyperintensities and grey matter volume...

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Detalles Bibliográficos
Autores principales:	Vipin, Ashwati, Kumar, Dilip, Soo, See Ann, Zailan, Fatin Zahra, Leow, Yi Jin, Koh, Chen Ling, Ng, Adeline Su Lyn, Ng, Kok Pin, Kandiah, Nagaendran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239168/ https://www.ncbi.nlm.nih.gov/pubmed/37270543 http://dx.doi.org/10.1186/s13195-023-01251-4

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