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APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia
BACKGROUND: White matter hyperintensities, a neuroimaging marker of small-vessel cerebrovascular disease and apolipoprotein ε4 (APOE4) allele, are important dementia risk factors. However, APOE4 as a key effect modifier in the relationship between white matter hyperintensities and grey matter volume...
Autores principales: | Vipin, Ashwati, Kumar, Dilip, Soo, See Ann, Zailan, Fatin Zahra, Leow, Yi Jin, Koh, Chen Ling, Ng, Adeline Su Lyn, Ng, Kok Pin, Kandiah, Nagaendran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239168/ https://www.ncbi.nlm.nih.gov/pubmed/37270543 http://dx.doi.org/10.1186/s13195-023-01251-4 |
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