Novel insights into systemic sclerosis using a sensitive computational method to analyze whole-genome bisulfite sequencing data

BACKGROUND: Abnormal DNA methylation is thought to contribute to the onset and progression of systemic sclerosis. Currently, the most comprehensive assay for profiling DNA methylation is whole-genome bisulfite sequencing (WGBS), but its precision depends on read depth and it may be subject to sequen...

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Detalles Bibliográficos
Autores principales: Yu, Jeffrey C. Y., Zeng, Yixiao, Zhao, Kaiqiong, Lu, Tianyuan, Oros Klein, Kathleen, Colmegna, Inés, Lora, Maximilien, Bhatnagar, Sahir R., Leask, Andrew, Greenwood, Celia M. T., Hudson, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239181/
https://www.ncbi.nlm.nih.gov/pubmed/37270501
http://dx.doi.org/10.1186/s13148-023-01513-w

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