Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review

BACKGROUND: Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may occur in up to 25% of patients, generally in the...

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Autores principales: Jiao, Wenyan, Wei, Li, Jiao, Fuyong, Pjetraj, Dorina, Feng, Jianying, Wang, Jvyan, Catassi, Carlo, Gatti, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239295/
https://www.ncbi.nlm.nih.gov/pubmed/37270515
http://dx.doi.org/10.1186/s13052-023-01478-9
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author Jiao, Wenyan
Wei, Li
Jiao, Fuyong
Pjetraj, Dorina
Feng, Jianying
Wang, Jvyan
Catassi, Carlo
Gatti, Simona
author_facet Jiao, Wenyan
Wei, Li
Jiao, Fuyong
Pjetraj, Dorina
Feng, Jianying
Wang, Jvyan
Catassi, Carlo
Gatti, Simona
author_sort Jiao, Wenyan
collection PubMed
description BACKGROUND: Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may occur in up to 25% of patients, generally in the second week of the disease. CASE PRESENTATION: We describe the case of KD developing in a 3-month infant, with an early occurrence of coronary artery aneurysm after only 3 days of fever, complicated by thrombosis, requiring aggressive treatments. CONCLUSIONS: Time of development of cardiac complications can be different in young infants with KD and both diagnostic criteria and treatment indications should be individualized in this class of age.
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spelling pubmed-102392952023-06-05 Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review Jiao, Wenyan Wei, Li Jiao, Fuyong Pjetraj, Dorina Feng, Jianying Wang, Jvyan Catassi, Carlo Gatti, Simona Ital J Pediatr Case Report BACKGROUND: Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may occur in up to 25% of patients, generally in the second week of the disease. CASE PRESENTATION: We describe the case of KD developing in a 3-month infant, with an early occurrence of coronary artery aneurysm after only 3 days of fever, complicated by thrombosis, requiring aggressive treatments. CONCLUSIONS: Time of development of cardiac complications can be different in young infants with KD and both diagnostic criteria and treatment indications should be individualized in this class of age. BioMed Central 2023-06-04 /pmc/articles/PMC10239295/ /pubmed/37270515 http://dx.doi.org/10.1186/s13052-023-01478-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Jiao, Wenyan
Wei, Li
Jiao, Fuyong
Pjetraj, Dorina
Feng, Jianying
Wang, Jvyan
Catassi, Carlo
Gatti, Simona
Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review
title Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review
title_full Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review
title_fullStr Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review
title_full_unstemmed Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review
title_short Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review
title_sort very early onset of coronary artery aneurysm in a 3-month infant with kawasaki disease: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239295/
https://www.ncbi.nlm.nih.gov/pubmed/37270515
http://dx.doi.org/10.1186/s13052-023-01478-9
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