Structural mapping of Na(v)1.7 antagonists

Voltage-gated sodium (Na(v)) channels are targeted by a number of widely used and investigational drugs for the treatment of epilepsy, arrhythmia, pain, and other disorders. Despite recent advances in structural elucidation of Na(v) channels, the binding mode of most Na(v)-targeting drugs remains un...

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Detalles Bibliográficos
Autores principales: Wu, Qiurong, Huang, Jian, Fan, Xiao, Wang, Kan, Jin, Xueqin, Huang, Gaoxingyu, Li, Jiaao, Pan, Xiaojing, Yan, Nieng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239435/
https://www.ncbi.nlm.nih.gov/pubmed/37270609
http://dx.doi.org/10.1038/s41467-023-38942-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239435/
https://www.ncbi.nlm.nih.gov/pubmed/37270609
http://dx.doi.org/10.1038/s41467-023-38942-3

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