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Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition
Within the chromatin, distal elements interact with promoters to regulate specific transcriptional programs. Histone acetylation, interfering with the net charges of the nucleosomes, is a key player in this regulation. Here, we report that the oncoprotein SET is a critical determinant for the levels...
Autores principales: | Zaghi, Mattia, Banfi, Federica, Massimino, Luca, Volpin, Monica, Bellini, Edoardo, Brusco, Simone, Merelli, Ivan, Barone, Cristiana, Bruni, Michela, Bossini, Linda, Lamparelli, Luigi Antonio, Pintado, Laura, D’Aliberti, Deborah, Spinelli, Silvia, Mologni, Luca, Colasante, Gaia, Ungaro, Federica, Cioni, Jean-Michel, Azzoni, Emanuele, Piazza, Rocco, Montini, Eugenio, Broccoli, Vania, Sessa, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239470/ https://www.ncbi.nlm.nih.gov/pubmed/37270547 http://dx.doi.org/10.1038/s41467-023-39043-x |
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