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A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels
The prevalence of light chain (AL) amyloidosis, characterized by the deposition of amyloid chains, is gradually increasing. The clinical features of the disease depend upon the location of amyloid deposition and can manifest in many forms. Although laboratory investigations can reveal proteinuria an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239556/ https://www.ncbi.nlm.nih.gov/pubmed/37284407 http://dx.doi.org/10.7759/cureus.38572 |
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author | Javed, Nismat Uday, Kalpana |
author_facet | Javed, Nismat Uday, Kalpana |
author_sort | Javed, Nismat |
collection | PubMed |
description | The prevalence of light chain (AL) amyloidosis, characterized by the deposition of amyloid chains, is gradually increasing. The clinical features of the disease depend upon the location of amyloid deposition and can manifest in many forms. Although laboratory investigations can reveal proteinuria and change in complement levels, hematuria and low complement levels are rarely reported. There are very few cases of renal AL amyloidosis presenting as persistent hematuria. We present the case of a 54-year-old female presenting with abdominal pain, proteinuria, and moderate persistent hematuria on admission who was later diagnosed with AL amyloidosis on biopsy. |
format | Online Article Text |
id | pubmed-10239556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-102395562023-06-05 A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels Javed, Nismat Uday, Kalpana Cureus Internal Medicine The prevalence of light chain (AL) amyloidosis, characterized by the deposition of amyloid chains, is gradually increasing. The clinical features of the disease depend upon the location of amyloid deposition and can manifest in many forms. Although laboratory investigations can reveal proteinuria and change in complement levels, hematuria and low complement levels are rarely reported. There are very few cases of renal AL amyloidosis presenting as persistent hematuria. We present the case of a 54-year-old female presenting with abdominal pain, proteinuria, and moderate persistent hematuria on admission who was later diagnosed with AL amyloidosis on biopsy. Cureus 2023-05-05 /pmc/articles/PMC10239556/ /pubmed/37284407 http://dx.doi.org/10.7759/cureus.38572 Text en Copyright © 2023, Javed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Javed, Nismat Uday, Kalpana A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels |
title | A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels |
title_full | A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels |
title_fullStr | A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels |
title_full_unstemmed | A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels |
title_short | A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels |
title_sort | case of isolated renal light chain amyloidosis with hematuria and low complement levels |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239556/ https://www.ncbi.nlm.nih.gov/pubmed/37284407 http://dx.doi.org/10.7759/cureus.38572 |
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