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A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels

The prevalence of light chain (AL) amyloidosis, characterized by the deposition of amyloid chains, is gradually increasing. The clinical features of the disease depend upon the location of amyloid deposition and can manifest in many forms. Although laboratory investigations can reveal proteinuria an...

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Detalles Bibliográficos
Autores principales: Javed, Nismat, Uday, Kalpana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239556/
https://www.ncbi.nlm.nih.gov/pubmed/37284407
http://dx.doi.org/10.7759/cureus.38572
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author Javed, Nismat
Uday, Kalpana
author_facet Javed, Nismat
Uday, Kalpana
author_sort Javed, Nismat
collection PubMed
description The prevalence of light chain (AL) amyloidosis, characterized by the deposition of amyloid chains, is gradually increasing. The clinical features of the disease depend upon the location of amyloid deposition and can manifest in many forms. Although laboratory investigations can reveal proteinuria and change in complement levels, hematuria and low complement levels are rarely reported. There are very few cases of renal AL amyloidosis presenting as persistent hematuria. We present the case of a 54-year-old female presenting with abdominal pain, proteinuria, and moderate persistent hematuria on admission who was later diagnosed with AL amyloidosis on biopsy.
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spelling pubmed-102395562023-06-05 A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels Javed, Nismat Uday, Kalpana Cureus Internal Medicine The prevalence of light chain (AL) amyloidosis, characterized by the deposition of amyloid chains, is gradually increasing. The clinical features of the disease depend upon the location of amyloid deposition and can manifest in many forms. Although laboratory investigations can reveal proteinuria and change in complement levels, hematuria and low complement levels are rarely reported. There are very few cases of renal AL amyloidosis presenting as persistent hematuria. We present the case of a 54-year-old female presenting with abdominal pain, proteinuria, and moderate persistent hematuria on admission who was later diagnosed with AL amyloidosis on biopsy. Cureus 2023-05-05 /pmc/articles/PMC10239556/ /pubmed/37284407 http://dx.doi.org/10.7759/cureus.38572 Text en Copyright © 2023, Javed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Javed, Nismat
Uday, Kalpana
A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels
title A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels
title_full A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels
title_fullStr A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels
title_full_unstemmed A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels
title_short A Case of Isolated Renal Light Chain Amyloidosis With Hematuria and Low Complement Levels
title_sort case of isolated renal light chain amyloidosis with hematuria and low complement levels
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239556/
https://www.ncbi.nlm.nih.gov/pubmed/37284407
http://dx.doi.org/10.7759/cureus.38572
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