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Amelioration of olfactory dysfunction in a mouse model of Parkinson’s disease via enhancing GABAergic signaling
BACKGROUND: Olfactory dysfunction is among the earliest non-motor symptoms of Parkinson’s disease (PD). As the foremost pathological hallmark, α-synuclein initiates the pathology in the olfactory pathway at the early stage of PD, particularly in the olfactory epithelium (OE) and olfactory bulb (OB)....
Autores principales: | Liu, Xing-Yang, Wang, Ke, Deng, Xian-Hua, Wei, Yi-Hua, Guo, Rui, Liu, Sui-Feng, Zhu, Yi-Fan, Zhong, Jia-Jun, Zheng, Jing-Yuan, Wang, Meng-Dan, Ye, Qiu-Hong, He, Jian-Quan, Guo, Kai-Hang, Zhu, Jun-Rong, Huang, Shu-Qiong, Chen, Ze-Xu, Lv, Chong-Shan, Wen, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239587/ https://www.ncbi.nlm.nih.gov/pubmed/37270503 http://dx.doi.org/10.1186/s13578-023-01049-9 |
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