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Development of an in vitro method for activation of X-succinate synthases for fumarate hydroalkylation

Anaerobic microbial degradation of hydrocarbons is often initiated through addition of the hydrocarbon to fumarate by enzymes known as X-succinate synthases (XSSs). XSSs use a glycyl radical cofactor, which is installed by an activating enzyme (XSS-AE), to catalyze this carbon-carbon coupling reacti...

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Detalles Bibliográficos
Autores principales: Andorfer, Mary C., King-Roberts, Devin T., Imrich, Christa N., Brotheridge, Balyn G., Drennan, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239695/
https://www.ncbi.nlm.nih.gov/pubmed/37283811
http://dx.doi.org/10.1016/j.isci.2023.106902

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