A pref-1-controlled non-inflammatory mechanism of insulin resistance

While insulin resistance (IR) is associated with inflammation in white adipose tissue, we report a non-inflammatory adipose mechanism of high fat-induced IR mediated by loss of Pref-1. Pref-1, released from adipose Pref-1+ cells with characteristics of M2 macrophages, endothelial cells or progenitor...

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Detalles Bibliográficos
Autores principales: Huang, Yiheng, Cui, Donghong, Chen, Liujun, Tong, Haibin, Wu, Hong, Muller, Grace K., Qi, Yadan, Wang, Shuxia, Xu, Jinjie, Gao, Xiang, Fifield, Kathleen E., Wang, Lingyan, Xia, Zhengyuan, Vanderluit, Jacqueline L., Liu, Suixin, Leng, Lin, Sun, Guang, McGuire, John, Young, Lawrence H., Bucala, Richard, Qi, Dake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239698/
https://www.ncbi.nlm.nih.gov/pubmed/37283810
http://dx.doi.org/10.1016/j.isci.2023.106923

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