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N6-methyl-2′-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis

Red blood cells supply the oxygen required for all human cells and are in demand for emerging blood-loss therapy. Here we identified N6-methyl-2′-deoxyadenosine (6mdA) as an agonist that promotes the hyperproliferation of burst-forming unit erythroid (BFU-E) progenitor cells. In addition, 6mdA repre...

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Detalles Bibliográficos
Autores principales: Li, Yao, Liang, Zi-Yu, Wang, Hai-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239700/
https://www.ncbi.nlm.nih.gov/pubmed/37283807
http://dx.doi.org/10.1016/j.isci.2023.106924