C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation

Dysregulated NLRP3 inflammasome activation drives a wide variety of diseases, while endogenous inhibition of this pathway is poorly characterised. The serum protein C4b-binding protein (C4BP) is a well-established inhibitor of complement with emerging functions as an endogenously expressed inhibitor...

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Detalles Bibliográficos
Autores principales: Bierschenk, Damien, Papac-Milicevic, Nikolina, Bresch, Ian P., Kovacic, Valentina, Bettoni, Serena, Dziedzic, Mateusz, Wetsel, Rick A., Eschenburg, Susanne, Binder, Christoph J., Blom, Anna M., King, Ben C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239802/
https://www.ncbi.nlm.nih.gov/pubmed/37283747
http://dx.doi.org/10.3389/fimmu.2023.1149822

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