Cargando…

Factors that influence a patient’s decision to engage in genetic research

INTRODUCTION: The most challenging step in clinical research studies is patient recruitment. Many research studies do not reach their targets because of participant rejection. The purpose of this study was to assess patient as well as the community knowledge, motivation, and barriers to participate...

Descripción completa

Detalles Bibliográficos
Autores principales: Almutairi, Amal, Alqubaishi, Fatimah Abdulrahman, Alsolm, Ebtehal A., Binowayn, Albandari, Almohammad, Rania, Wani, Tariq, Ababtain, Aljohara, Alkadi, Udai, Alrashed, May M., Althagafi, Malak, Abu-Safieh, Leen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239877/
https://www.ncbi.nlm.nih.gov/pubmed/37283985
http://dx.doi.org/10.3389/fpubh.2023.865786
_version_ 1785053590878945280
author Almutairi, Amal
Alqubaishi, Fatimah Abdulrahman
Alsolm, Ebtehal A.
Binowayn, Albandari
Almohammad, Rania
Wani, Tariq
Ababtain, Aljohara
Alkadi, Udai
Alrashed, May M.
Althagafi, Malak
Abu-Safieh, Leen
author_facet Almutairi, Amal
Alqubaishi, Fatimah Abdulrahman
Alsolm, Ebtehal A.
Binowayn, Albandari
Almohammad, Rania
Wani, Tariq
Ababtain, Aljohara
Alkadi, Udai
Alrashed, May M.
Althagafi, Malak
Abu-Safieh, Leen
author_sort Almutairi, Amal
collection PubMed
description INTRODUCTION: The most challenging step in clinical research studies is patient recruitment. Many research studies do not reach their targets because of participant rejection. The purpose of this study was to assess patient as well as the community knowledge, motivation, and barriers to participate in genetic research. METHODS: A cross-section study was conducted between September 2018 and February 2020 using face-to-face interviews with candidate patients from outpatient clinics at King Fahad Medical City (KFMC), Riyadh, Saudi Arabia. Additionally, an online survey was conducted to assess the community’s knowledge, motivation and barriers to participate in genetic research studies. RESULTS: In total, 470 patients were interviewed for this study, with 341 being successfully recruited for the face to face interview, and the other patients being refused owing to time constraints. The majority percentage of the respondents were females. The respondents’ mean age was 30, and 52.6% reported having a college degree. The survey results from 388 participants illustrated that around 90% of the participants, participated voluntarily due to a good understanding of genetics studies. The majority held positive attitudes toward being part of genetic research, which exceeded the reported motivation score of >75%. The survey indicated that >90% of individuals were willing to participate to acquire therapeutic benefits or to receive continued aftercare. However, 54.6% of survey participants were worried about the side effects and the risks involved in genetic testing. A higher proportion (71.4%) of respondents reported that lack of knowledge about genetic research was one of the barriers to rejecting participation. CONCLUSION: Respondents reported relatively high motivation and knowledge for participation in genetic research. However, study participants reported “do not know enough about genetic research” and “lack of time during clinic visit” as a barrier for participation in genetic research.
format Online
Article
Text
id pubmed-10239877
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-102398772023-06-06 Factors that influence a patient’s decision to engage in genetic research Almutairi, Amal Alqubaishi, Fatimah Abdulrahman Alsolm, Ebtehal A. Binowayn, Albandari Almohammad, Rania Wani, Tariq Ababtain, Aljohara Alkadi, Udai Alrashed, May M. Althagafi, Malak Abu-Safieh, Leen Front Public Health Public Health INTRODUCTION: The most challenging step in clinical research studies is patient recruitment. Many research studies do not reach their targets because of participant rejection. The purpose of this study was to assess patient as well as the community knowledge, motivation, and barriers to participate in genetic research. METHODS: A cross-section study was conducted between September 2018 and February 2020 using face-to-face interviews with candidate patients from outpatient clinics at King Fahad Medical City (KFMC), Riyadh, Saudi Arabia. Additionally, an online survey was conducted to assess the community’s knowledge, motivation and barriers to participate in genetic research studies. RESULTS: In total, 470 patients were interviewed for this study, with 341 being successfully recruited for the face to face interview, and the other patients being refused owing to time constraints. The majority percentage of the respondents were females. The respondents’ mean age was 30, and 52.6% reported having a college degree. The survey results from 388 participants illustrated that around 90% of the participants, participated voluntarily due to a good understanding of genetics studies. The majority held positive attitudes toward being part of genetic research, which exceeded the reported motivation score of >75%. The survey indicated that >90% of individuals were willing to participate to acquire therapeutic benefits or to receive continued aftercare. However, 54.6% of survey participants were worried about the side effects and the risks involved in genetic testing. A higher proportion (71.4%) of respondents reported that lack of knowledge about genetic research was one of the barriers to rejecting participation. CONCLUSION: Respondents reported relatively high motivation and knowledge for participation in genetic research. However, study participants reported “do not know enough about genetic research” and “lack of time during clinic visit” as a barrier for participation in genetic research. Frontiers Media S.A. 2023-05-22 /pmc/articles/PMC10239877/ /pubmed/37283985 http://dx.doi.org/10.3389/fpubh.2023.865786 Text en Copyright © 2023 Almutairi, Alqubaishi, Alsolm, Binowayn, Almohammad, Wani, Ababtain, Alkadi, Alrashed, Althagafi and Abu-Safieh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Almutairi, Amal
Alqubaishi, Fatimah Abdulrahman
Alsolm, Ebtehal A.
Binowayn, Albandari
Almohammad, Rania
Wani, Tariq
Ababtain, Aljohara
Alkadi, Udai
Alrashed, May M.
Althagafi, Malak
Abu-Safieh, Leen
Factors that influence a patient’s decision to engage in genetic research
title Factors that influence a patient’s decision to engage in genetic research
title_full Factors that influence a patient’s decision to engage in genetic research
title_fullStr Factors that influence a patient’s decision to engage in genetic research
title_full_unstemmed Factors that influence a patient’s decision to engage in genetic research
title_short Factors that influence a patient’s decision to engage in genetic research
title_sort factors that influence a patient’s decision to engage in genetic research
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239877/
https://www.ncbi.nlm.nih.gov/pubmed/37283985
http://dx.doi.org/10.3389/fpubh.2023.865786
work_keys_str_mv AT almutairiamal factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT alqubaishifatimahabdulrahman factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT alsolmebtehala factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT binowaynalbandari factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT almohammadrania factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT wanitariq factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT ababtainaljohara factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT alkadiudai factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT alrashedmaym factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT althagafimalak factorsthatinfluenceapatientsdecisiontoengageingeneticresearch
AT abusafiehleen factorsthatinfluenceapatientsdecisiontoengageingeneticresearch