SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans

Introduction: The high prevalence of neurodegenerative diseases in our population and the lack of effective treatments encourage the search for new therapeutic targets for these pathologies. We have recently described that submaximal inhibition of the Sarco-Endoplasmic Reticulum Ca(2+) ATPase (SERCA...

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Detalles Bibliográficos
Autores principales: Romero-Sanz, Silvia, Caldero-Escudero, Elena, Álvarez-Illera, Pilar, Santo-Domingo, Jaime, Fonteriz, Rosalba I., Montero, Mayte, Álvarez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239880/
https://www.ncbi.nlm.nih.gov/pubmed/37284303
http://dx.doi.org/10.3389/fphar.2023.1182428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239880/
https://www.ncbi.nlm.nih.gov/pubmed/37284303
http://dx.doi.org/10.3389/fphar.2023.1182428

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