Identifying promising GSK3β inhibitors for cancer management: a computational pipeline combining virtual screening and molecular dynamics simulations

Glycogen synthase kinase-3 (GSK3β), a serine/threonine protein kinase, has been discovered as a novel target for anticancer drugs. Although GSK3β is involved in multiple pathways linked to the etiology of various cancers, no specific GSK3β inhibitor has been authorized for cancer therapy. Most of it...

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Detalles Bibliográficos
Autores principales: Hua, Libo, Anjum, Farah, Shafie, Alaa, Ashour, Amal Adnan, Almalki, Abdulraheem Ali, Alqarni, Ali Abdullah, Banjer, Hamsa Jameel, Almaghrabi, Sarah Abdullah, He, Shan, Xu, Nenggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239944/
https://www.ncbi.nlm.nih.gov/pubmed/37284581
http://dx.doi.org/10.3389/fchem.2023.1200490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239944/
https://www.ncbi.nlm.nih.gov/pubmed/37284581
http://dx.doi.org/10.3389/fchem.2023.1200490

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