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EGFR and ERBB2 exon 20 insertion/duplication in advanced non–small cell lung cancer: genomic profiling and clinicopathologic features

BACKGROUND: Exon 20 (ex20) in-frame insertions or duplications (ins/dup) in epidermal growth factor receptor (EGFR) and its analog erb-b2 receptor tyrosine kinase 2 (ERBB2) are each detected in 1.5% of non–small cell lung cancer (NSCLC). Unlike EGFR p.L858R or ex19 deletions, ex20 ins/dup is associa...

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Detalles Bibliográficos
Autores principales:	Sompallae, Ramakrishna R., Dundar, Bilge, Guseva, Natalya V., Bossler, Aaron D., Ma, Deqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239961/ https://www.ncbi.nlm.nih.gov/pubmed/37284196 http://dx.doi.org/10.3389/fonc.2023.1163485

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