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Puerarin inhibited oxidative stress and alleviated cerebral ischemia-reperfusion injury through PI3K/Akt/Nrf2 signaling pathway

Introduction: Puerarin (PUE) is a natural compound isolated from Puerariae Lobatae Radix, which has a neuroprotective effect on IS. We explored the therapeutic effect and underlying mechanism of PUE on cerebral I/R injury by inhibiting oxidative stress related to the PI3K/Akt/Nrf2 pathway in vitro a...

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Detalles Bibliográficos
Autores principales:	Zhang, Qianqian, Yao, Min, Qi, Jiajia, Song, Rui, Wang, Lei, Li, Jiacheng, Zhou, Xian, Chang, Dennis, Huang, Qi, Li, Lili, Wang, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240043/ https://www.ncbi.nlm.nih.gov/pubmed/37284311 http://dx.doi.org/10.3389/fphar.2023.1134380

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