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Could METS-VF provide a clue as to the formation of kidney stones?

OBJECTIVE: The lifetime occurrence rate of kidney stones is 14%, making it one of the most prevalent urological conditions. Other contributing elements, such as obesity, diabetes, diet, and heredity, are also taken into account. Our research sought to explore the potential link between high visceral...

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Autores principales: Guo, Zhenyu, Li, Guoxiang, Chen, Yan, Fan, Shuai, Sun, Shuai, Hao, Yunwu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240079/
https://www.ncbi.nlm.nih.gov/pubmed/37284217
http://dx.doi.org/10.3389/fendo.2023.1166922
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author Guo, Zhenyu
Li, Guoxiang
Chen, Yan
Fan, Shuai
Sun, Shuai
Hao, Yunwu
Wang, Wei
author_facet Guo, Zhenyu
Li, Guoxiang
Chen, Yan
Fan, Shuai
Sun, Shuai
Hao, Yunwu
Wang, Wei
author_sort Guo, Zhenyu
collection PubMed
description OBJECTIVE: The lifetime occurrence rate of kidney stones is 14%, making it one of the most prevalent urological conditions. Other contributing elements, such as obesity, diabetes, diet, and heredity, are also taken into account. Our research sought to explore the potential link between high visceral fat scores (METS-VF) and the occurrence of kidney stones, as a means of understanding how to prevent them. METHODS: This research utilized data from the National Health and Nutrition Examination Survey (NHANES), mirroring the demographics of the United States. We carried out an in-depth analysis of the connection between METS-VF and kidney stones, based on data from 29,246 participants in the National Health and Nutrition Examination Survey spanning 2007 to 2018, involving logistic regression, segmentation, and dose-response curve analysis. RESULTS: Our study of 29,246 potential participants found that METS-VF was positively associated with the prevalence and progression of kidney stones. After subgroup analysis by gender, race, blood pressure, and blood glucose, our results showed that the ORs for METS-VF and kidney stones were (1.49, 1.44) in males and females, respectively; while in Mexicans, whites, blacks, and In other populations, the OR values were (1.33, 1.43, 1.54, 1.86); in hypertensive and normal populations, the OR values were (1.23, 1.48); in diabetic patients and normoglycemic patients were (1.36,1.43). This proves that it works for all groups of people. SUMMARY: Our studies demonstrate a strong connection between METS-FV and the emergence of kidney stones. It would be beneficial to investigate METS-VF as a marker for kidney stone development and progression in light of these findings.
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spelling pubmed-102400792023-06-06 Could METS-VF provide a clue as to the formation of kidney stones? Guo, Zhenyu Li, Guoxiang Chen, Yan Fan, Shuai Sun, Shuai Hao, Yunwu Wang, Wei Front Endocrinol (Lausanne) Endocrinology OBJECTIVE: The lifetime occurrence rate of kidney stones is 14%, making it one of the most prevalent urological conditions. Other contributing elements, such as obesity, diabetes, diet, and heredity, are also taken into account. Our research sought to explore the potential link between high visceral fat scores (METS-VF) and the occurrence of kidney stones, as a means of understanding how to prevent them. METHODS: This research utilized data from the National Health and Nutrition Examination Survey (NHANES), mirroring the demographics of the United States. We carried out an in-depth analysis of the connection between METS-VF and kidney stones, based on data from 29,246 participants in the National Health and Nutrition Examination Survey spanning 2007 to 2018, involving logistic regression, segmentation, and dose-response curve analysis. RESULTS: Our study of 29,246 potential participants found that METS-VF was positively associated with the prevalence and progression of kidney stones. After subgroup analysis by gender, race, blood pressure, and blood glucose, our results showed that the ORs for METS-VF and kidney stones were (1.49, 1.44) in males and females, respectively; while in Mexicans, whites, blacks, and In other populations, the OR values were (1.33, 1.43, 1.54, 1.86); in hypertensive and normal populations, the OR values were (1.23, 1.48); in diabetic patients and normoglycemic patients were (1.36,1.43). This proves that it works for all groups of people. SUMMARY: Our studies demonstrate a strong connection between METS-FV and the emergence of kidney stones. It would be beneficial to investigate METS-VF as a marker for kidney stone development and progression in light of these findings. Frontiers Media S.A. 2023-05-22 /pmc/articles/PMC10240079/ /pubmed/37284217 http://dx.doi.org/10.3389/fendo.2023.1166922 Text en Copyright © 2023 Guo, Li, Chen, Fan, Sun, Hao and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Guo, Zhenyu
Li, Guoxiang
Chen, Yan
Fan, Shuai
Sun, Shuai
Hao, Yunwu
Wang, Wei
Could METS-VF provide a clue as to the formation of kidney stones?
title Could METS-VF provide a clue as to the formation of kidney stones?
title_full Could METS-VF provide a clue as to the formation of kidney stones?
title_fullStr Could METS-VF provide a clue as to the formation of kidney stones?
title_full_unstemmed Could METS-VF provide a clue as to the formation of kidney stones?
title_short Could METS-VF provide a clue as to the formation of kidney stones?
title_sort could mets-vf provide a clue as to the formation of kidney stones?
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240079/
https://www.ncbi.nlm.nih.gov/pubmed/37284217
http://dx.doi.org/10.3389/fendo.2023.1166922
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